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Potential mechanisms of disease progression and management of advanced-phase chronic myeloid leukemia

20 Sept 2013

Abstract excerpt

Despite vast improvements in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (CML) in chronic phase (CP), advanced stages of CML, accelerated phase or blast crisis, remain notoriously difficult to treat. Treatments that are highly effective against CML-CP produce disappointing results against advanced disease. Therefore, a primary goal of therapy should be to maintain patients in CP for...

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PMID: 24050507
DOI: 10.3109/10428194.2013.845883

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