Article
Distinguishing the rates of gene activation from phenotypic variations.
BMC systems biology - 18 Jun 2015
Chen Ye, Lv Cheng, Li Fangting, Li Tiejun
Abstract excerpt
BACKGROUND: Stochastic genetic switching driven by intrinsic noise is an important process in gene expression. When the rates of gene activation/inactivation are relatively slow, fast, or medium compared with the synthesis/degradation rates of mRNAs and proteins, the variability of protein and mRNA levels may exhibit very different dynamical patterns. It is desirable to provide a systematic approach to identify...
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