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Article

The impact of polymorphic variations in the 5p15, 6p12, 6p21 and 15q25 Loci on the risk and prognosis of portuguese patients with non-small cell lung cancer.

PloS one - 1 Jan 2013

de Mello Ramon Andrade, Ferreira Mónica, Soares-Pires Filipa, Costa Sandra, Cunha João, Oliveira Pedro, Hespanhol Venceslau, Reis Rui Manuel

Abstract excerpt

INTRODUCTION: Polymorphic variants in the 5p15, 6p12, 6p21, and 15q25 loci were demonstrated to potentially contribute to lung cancer carcinogenesis. Therefore, this study was performed to assess the role of those variants in non-small cell lung cancer (NSCLC) risk and prognosis in a Portuguese population. MATERIALS AND METHODS: Blood from patients with NSCLC was prospectively collected. To perform an association...

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PMID: 24039754
DOI: 10.1371/journal.pone.0072373
PMCID: PMC3765163

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