Article
The Aspergillus nidulans npeA locus consists of three contiguous genes required for penicillin biosynthesis.
The EMBO journal - 1 Jan 1990
MacCabe A P, Riach M B, Unkles S E, Kinghorn J R
Abstract excerpt
Clones of Aspergillus nidulans genomic DNA spanning 20 kb have been isolated and shown by a combination of classical and molecular genetic means to represent the npeA locus, previously found to be one of four loci (npeA, npeB, npeC and npeD) involved in the synthesis of penicillin. As well as con...
Topics
- Aspergillus nidulans
- Cloning, Molecular
- DNA, Fungal
- Enzymes
- Genes, Fungal
- Mutation
- Nucleic Acid Hybridization
- Oxidoreductases
- Penicillins
- Peptide Synthases
- Plasmids
- Promoter Regions, Genetic
- RNA, Messenger
- Restriction Mapping
- Transcription, Genetic