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Article

Higher therapeutic CsA levels early post transplantation reduce risk of acute GVHD and improves survival.

Bone marrow transplantation - 1 Jan 2014

Rogosheske J R, Fargen A D, DeFor T E, Warlick E, Arora M, Blazar B R, Weisdorf D J, Brunstein C G

Abstract excerpt

We studied whether early CsA trough levels were associated with the risk of acute GVHD in 337 patients after either sibling PBSC or double umbilical cord blood transplantation. All patients, regardless of donor type, started CsA at a dose of 5 mg/kg i.v. divided twice daily, targeting trough concentrations 200-400 ng/mL. The CsA level was studied by a weighted average method calculated by giving 70% of the weight...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24037024
DOI: 10.1038/bmt.2013.139
PMCID: PMC3947241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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