Article
Impact of cyclosporine levels on the development of acute graft versus host disease after reduced intensity conditioning allogeneic stem cell transplantation.
Mediators of inflammation - 1 Jan 2014
García Cadenas Irene, Valcarcel David, Martino Rodrigo, Piñana J L, Barba Pere, Novelli Silvana, Esquirol Albert, Garrido Ana, Saavedra Silvana, Granell Miquel, Moreno Carol, Briones Javier, Brunet Salut, Sierra Jorge
Abstract excerpt
We analyze the impact of cyclosporine (CsA) levels in the development of acute graft-versus-host disease (aGVHD) after reduced intensity conditioning allogeneic hematopoietic transplantation (allo-RIC). We retrospectively evaluated 156 consecutive patients who underwent HLA-identical sibling allo-RIC at our institution. CsA median blood levels in the 1st, 2nd, 3rd and 4th weeks after allo-RIC were 134 (range:...
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