Article
The 2-oxoglutarate supply exerts significant control on the lysine synthesis flux in Saccharomyces cerevisiae.
The FEBS journal - 1 Nov 2013
Quezada Héctor, Marín-Hernández Alvaro, Arreguín-Espinosa Roberto, Rumjanek Franklin D, Moreno-Sánchez Rafael, Saavedra Emma
Abstract excerpt
To determine the extent to which the supply of the precursor 2-oxoglutarate (2-OG) controls the synthesis of lysine in Saccharomyces cerevisiae growing exponentially in high glucose, top-down elasticity analysis was used. Three groups of reactions linked by 2-OG were defined. The 2-OG supply grou...
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