Article
Heritability analyses show visit-to-visit blood pressure variability reflects different pathological phenotypes in younger and older adults: evidence from UK twins.
Journal of hypertension - 1 Dec 2013
Menni Cristina, Mangino Massimo, Zhang Feng, Clement Gail, Snieder Harold, Padmanabhan Sandosh, Spector Tim D
Abstract excerpt
BACKGROUND: Clinic and long-term average blood pressure (BP) are heritable traits with estimates of heritability ranging from 0.31 to 0.68. Long-term visit-to-visit BP variability (BPV) is emerging as a new cardiovascular risk predictor, though it is unclear if this is completely independent of BP. We hypothesize that BPV should demonstrate the same pattern of additive genetic, shared environmental and unique...
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