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Modeling human skeletal development using human pluripotent stem cells

1 May 2023

Abstract excerpt

Chondrocytes and osteoblasts differentiated from induced pluripotent stem cells (iPSCs) will provide insights into skeletal development and genetic skeletal disorders and will generate cells for regenerative medicine applications. Here, we describe a method that directs iPSC-derived sclerotome to chondroprogenitors in 3D pellet culture then to articular chondrocytes or, alternatively, along the growth plate...

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PMID: 37126720
DOI: 10.1073/pnas.2211510120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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