Article
SNP analysis using a molecular beacon-based operating cooperatively (OC) sensor.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Cornett Evan M, Kolpashchikov Dmitry M
Abstract excerpt
Analysis of single-nucleotide polymorphisms (SNPs) is important for diagnosis of infectious and genetic diseases, for environment and population studies, as well as in forensic applications. Herein is a detailed description to design an "operating cooperatively" (OC) sensor for highly specific SNP analysis. OC sensors use two unmodified DNA adaptor strands and a molecular beacon probe to detect a nucleic acid...
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