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Article

Mitochondrial uptake of thiamin pyrophosphate: physiological and cell biological aspects.

PloS one - 1 Jan 2013

Subramanian Veedamali S, Nabokina Svetlana M, Lin-Moshier Yaping, Marchant Jonathan S, Said Hamid M

Abstract excerpt

Mammalian cells obtain vitamin B1 (thiamin) from their surrounding environment and convert it to thiamin pyrophosphate (TPP) in the cytoplasm. Most of TPP is then transported into the mitochondria via a carrier-mediated process that involves the mitochondrial thiamin pyrophosphate transporter (MTPPT). Knowledge about the physiological parameters of the MTPP-mediated uptake process, MTPPT targeting and the impact...

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Identifiers

PMID: 24023687
DOI: 10.1371/journal.pone.0073503
PMCID: PMC3758298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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