Article
Prognostic value of nuclear translocation of aryl hydrocarbon receptor for non-small cell lung cancer.
Anticancer research - 1 Sept 2013
Su Jang-Ming, Lin Pinpin, Chang Han
Abstract excerpt
BACKGROUND: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor which translocates from the cytoplasm to the nucleus after activation. AhR overexpression is positively associated with epidermal growth factor (EGFR) expression in non-small cell lung cancer (NSCLC). The association between AhR expression and types of EGFR mutation, and the prognostic value of AhR expression in NSCLC...
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