Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aryl hydrocarbon receptor mediates Jak2/STAT3 signaling for non-small cell lung cancer stem cell maintenance.

Experimental cell research - 1 Nov 2020

Xiong Jie, Zhang Xinxin, Zhang Yong, Wu Bin, Fang Liang, Wang Ning, Yi Hongyu, Chang Ning, Chen Lihua, Zhang Jian

Abstract excerpt

Cancer stem cells (CSCs) play an important role in shaping the invasive cancer phenotype by contributing to tumor initiation, metastasis, relapse, and therapeutic resistance in non-small cell lung cancer (NSCLC). The Aryl hydrocarbon receptor (AhR), a ligand activated transcription factor, which is well known for mediating the toxicity and tumorigenesis of a variety of environmental pollutants, has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Azo Compounds
Share to Carcinogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kynurenine

Share to Neoplastic Stem Cells

Share to Nitriles

Share to Pyrazoles

Share to Receptors, Aryl Hydrocarbon

Share to STAT3 Transcription Factor

Source

Identifiers

PMID: 32941808
DOI: 10.1016/j.yexcr.2020.112288

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aryl hydrocarbon receptor mediates Jak2/STAT3 signaling for non-small cell lung cancer stem cell maintenance.PMID 32941808Read ↗

Epigenetic Regulation of Cancer Stem Cells by the Aryl Hydrocarbon Receptor PathwaySemantic proximity Read ↗

Activation of AhR with nuclear IKKα regulates cancer stem-like properties in the occurrence of radioresistance.Semantic proximity Read ↗

The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cellsSemantic proximity Read ↗

Role of STAT3 in lung cancerSemantic proximity Read ↗

E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent mannerSemantic proximity Read ↗

Oncogenic potential of human pluripotent stem cell‐derived lung organoids with HER2 overexpressionSemantic proximity Read ↗

Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cellsSemantic proximity Read ↗

Small cell lung cancer: significance of RB alterations and TTF-1 expression in its carcinogenesis, phenotype, and biology.Semantic proximity Read ↗

High expression of octamer-binding transcription factor 4A, prominin-1 and aldehyde dehydrogenase strongly indicates involvement in the initiation of lung adenocarcinoma resulting in shorter disease-free intervalsSemantic proximity Read ↗

Prognostic significance of stem cell-related marker expression and its correlation with histologic subtypes in lung adenocarcinomaSemantic proximity Read ↗

AhR and STAT3: A Dangerous Duo in Chemical CarcinogenesisSemantic proximity Read ↗

Novel Primary Human Cancer Stem-Like Cell Populations from Non-Small Cell Lung Cancer: Inhibition of Cell Survival by Targeting NF-κB and MYC Signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.