Article
Effects of exogenous alpha-synuclein on stimulated dopamine overflow in dorsal striatum.
Neuroscience letters - 25 Oct 2013
Pelkonen Anssi, Kallunki Pekka, Yavich Leonid
Abstract excerpt
Alpha-synuclein (α-syn) is mainly a presynaptic protein that has been implicated in Parkinson's disease and various other neurodegenerative disorders. Evidence obtained in knockout mice suggests that α-syn controls plasticity of dopamine (DA) overflow in presynaptic terminals. It is also believed that α-syn spreads and may seed its aggregates from cell to cell. The effects of exogenously applied α-syn on...
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