Article

Structural basis of Rgg protein binding to their regulatory pheromones and target DNA promoters

2020-04-30

Abstract excerpt

Rgg family proteins, such as Rgg2 and Rgg3, have emerged as primary quorum-sensing regulated transcription factors in Streptococcus species, controlling virulence, antimicrobial resistance, and biofilm formation. Rgg2 and Rgg3 function is regulated by their interaction with oligopeptide quorum-sensing signals called short hydrophobic peptides (SHPs). The molecular basis of Rgg-SHP and Rgg-target DNA promoter spec...

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Literature Corpus work: 424118ec-f618-59a3-bebe-9307b1e0361e
DOI: 10.1101/2020.04.30.069369

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