Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ciprofloxacin treatment failure in a murine model of pyelonephritis due to an AAC(6')-Ib-cr-producing Escherichia coli strain susceptible to ciprofloxacin in vitro.

Antimicrobial agents and chemotherapy - 1 Dec 2013

Guillard T, Cambau E, Chau F, Massias L, de Champs C, Fantin B

Abstract excerpt

AAC(6')-Ib-cr is a plasmid-mediated quinolone resistance mechanism described worldwide for Escherichia coli. Since it confers in vitro only a low level of resistance to ciprofloxacin, we evaluated its impact on the in vivo activity of ciprofloxacin. Isogenic strains were obtained by transferring...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ciprofloxacin
Share to DNA Gyrase
Share to Drug Administration Schedule

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Escherichia coli Infections

Share to Mice, Inbred CBA

Share to Pyelonephritis

Share to Transformation, Bacterial

Share to Treatment Failure

Source

Open in PubMed Open full text

Identifiers

PMID: 24018262
DOI: 10.1128/AAC.01489-13
PMCID: PMC3837926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24018262-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Ciprofloxacin treatment failure in a murine model of pyelonephritis due to an AAC(6')-Ib-cr-producing Escherichia coli strain susceptible to ciprofloxacin in vitro.PMID 24018262Read ↗

Plasmidic qnrA3 Enhances Escherichia coli Fitness in Absence of Antibiotic ExposureSemantic proximity Read ↗

New Plasmid-Mediated Fluoroquinolone Efflux Pump, QepA, Found in an Escherichia coli Clinical IsolateSemantic proximity Read ↗

Characterization of fluoroquinolone-resistant mutants of escherichia coli selected in vitro.Semantic proximity Read ↗

MECHANISMS OF RESISTANCE TO CIPROFLOXACIN AND GENETIC DIVERSITY OF ESCHERICHIA COLI STRAINS ORIGINATING FROM URINE CULTURES PERFORMED FOR ROMANIAN ADULTS.Semantic proximity Read ↗

Mechanisms of fluoroquinolone resistance among Escherichia coli isolates from urinary tract infections in ThailandSemantic proximity Read ↗

Multiple mechanisms contributing to ciprofloxacin resistance among Gram negative bacteria causing infections to cancer patientsSemantic proximity Read ↗

High frequency of aac(6')-Ib-cr gene associated with double mutations in gyrA and parC in Escherichia coli isolates from patients with urinary tract infections.Semantic proximity Read ↗

Impact of low-level fluoroquinolone resistance genes qnrA1, qnrB19 and qnrS1 on ciprofloxacin treatment of isogenic Escherichia coli strains in a murine urinary tract infection model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.