Multiple mechanisms contributing to ciprofloxacin resistance among Gram negative bacteria causing infections to cancer patients

doi:10.1038/s41598-018-30756-4

Article

Multiple mechanisms contributing to ciprofloxacin resistance among Gram negative bacteria causing infections to cancer patients

10 Aug 2018

Abstract excerpt

Fluoroquinolones have been used for prophylaxis against infections in cancer patients but their impact on the resistance mechanisms still require further investigation. To elucidate mechanisms underlying ciprofloxacin (CIP) resistance in Gram-negative pathogens causing infections to cancer patients, 169 isolates were investigated. Broth microdilution assays showed high-level CIP resistance in 89.3% of the...

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