Article
Genetic background may contribute to PAM50 gene expression breast cancer subtype assignments.
PloS one - 1 Jan 2013
Hu Ying, Bai Ling, Geiger Thomas, Goldberger Natalie, Walker Renard C, Green Jeffery E, Wakefield Lalage M, Hunter Kent W
Abstract excerpt
Recent advances in genome wide transcriptional analysis have provided greater insights into the etiology and heterogeneity of breast cancer. Molecular signatures have been developed that stratify the conventional estrogen receptor positive or negative categories into subtypes that are associated with differing clinical outcomes. It is thought that the expression patterns of the molecular subtypes primarily...
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