Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Periostin contributes to the acquisition of multipotent stem cell-like properties in human mammary epithelial cells and breast cancer cells.

PloS one - 1 Jan 2013

Wang Xiaowei, Liu Jia, Wang Zhe, Huang Yangmei, Liu Weiping, Zhu Xiao, Cai Yao, Fang Xiaoguang, Lin Shuyong, Yuan Li, Ouyang Gaoliang

Abstract excerpt

Periostin (POSTN), a recently characterised matricellular protein, is frequently dysregulated in various malignant cancers and promotes tumor metastatic growth. POSTN plays a critical role in the crosstalk between murine breast cancer stem cells (CSCs) and their niche to permit metastatic colonization. However, whether pro-metastatic capability of POSTN is associated with multipotent potentials of mesenchymal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mesenchymal Stem Cells

Share to Multipotent Stem Cells

Share to Muscle Development

Share to Neoplastic Stem Cells

Share to Osteoblasts

Share to Tumor Burden

Source

Open in PubMed Open full text

Identifiers

PMID: 24009721
DOI: 10.1371/journal.pone.0072962
PMCID: PMC3756944

Genes

POSTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Periostin contributes to the acquisition of multipotent stem cell-like properties in human mammary epithelial cells and breast cancer cells.PMID 24009721Read ↗

Periostin: biology and function in cancerSemantic proximity Read ↗

Periostin: A Matricellular Protein With Multiple Functions in Cancer Development and ProgressionSemantic proximity Read ↗

Periostin gene expression in neu-positive breast cancer cells is regulated by a FGFR signaling cross talk with TGFβ/PI3K/AKT pathwaysSemantic proximity Read ↗

Periostin promotes the proliferation and metastasis of osteosarcoma by increasing cell survival and activates the PI3K/Akt pathwaySemantic proximity Read ↗

Periostin facilitates ovarian cancer recurrence by enhancing cancer stemness.Semantic proximity Read ↗

Acquired Expression of Periostin by Human Breast Cancers Promotes Tumor Angiogenesis through Up-Regulation of Vascular Endothelial Growth Factor Receptor 2 ExpressionSemantic proximity Read ↗

Periostin <sup>+</sup> stromal cells guide lymphovascular invasion by cancer cellsSemantic proximity Read ↗

Periostin facilitates ovarian cancer recurrence by enhancing cancer stemnessSemantic proximity Read ↗

Periostin is associated with prognosis and immune cell infiltration in pancreatic adenocarcinoma based on integrated bioinformatics analysisSemantic proximity Read ↗

The multifaceted role of periostin in tumorigenesisSemantic proximity Read ↗

Periostin shows increased evolutionary plasticity in its alternatively spliced regionSemantic proximity Read ↗

Loss of periostin/OSF-2 in ErbB2/Neu-driven tumors results in androgen receptor-positive molecular apocrine-like tumors with reduced Notch1 activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.