Article

Periostin facilitates ovarian cancer recurrence by enhancing cancer stemness

2023-04-02

Abstract excerpt

Ovarian cancer (OC) is the deadliest reproductive system cancer. Its high lethality is due to the high recurrence rate and the development of chemotherapeutic resistance, which requires synergy between cancer cells and non-cancerous cells of the tumor microenvironment (TME). Analysis of gene expression microarray data from paired primary and recurrent OC tissues revealed significantly elevated expression of the ge...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 606b6ae4-bf03-5618-b7dd-3fa8c0c6b0fd
DOI: 10.1101/2023.03.30.534465

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Periostin facilitates ovarian cancer recurrence by enhancing cancer stemnessDOI 10.1101/2023.03.30.534465Read

Periostin facilitates ovarian cancer recurrence by enhancing cancer stemness.Semantic proximity Read

Upregulation of Periostin and Reactive Stroma Is Associated with Primary Chemoresistance and Predicts Clinical Outcomes in Epithelial Ovarian CancerSemantic proximity Read

Periostin contributes to the acquisition of multipotent stem cell-like properties in human mammary epithelial cells and breast cancer cells.Semantic proximity Read

Periostin promotes the proliferation and metastasis of osteosarcoma by increasing cell survival and activates the PI3K/Akt pathwaySemantic proximity Read

Periostin gene expression in neu-positive breast cancer cells is regulated by a FGFR signaling cross talk with TGFβ/PI3K/AKT pathwaysSemantic proximity Read

Periostin: biology and function in cancerSemantic proximity Read

Loss of periostin/OSF-2 in ErbB2/Neu-driven tumors results in androgen receptor-positive molecular apocrine-like tumors with reduced Notch1 activity.Semantic proximity Read

Periostin is associated with prognosis and immune cell infiltration in pancreatic adenocarcinoma based on integrated bioinformatics analysisSemantic proximity Read

Acquired Expression of Periostin by Human Breast Cancers Promotes Tumor Angiogenesis through Up-Regulation of Vascular Endothelial Growth Factor Receptor 2 ExpressionSemantic proximity Read

The multifaceted role of periostin in tumorigenesisSemantic proximity Read

MSC stimulate ovarian tumor growth during intercellular communication but reduce tumorigenicity after fusion with ovarian cancer cellsSemantic proximity Read

Characterization of periostin isoform pattern in non-small cell lung cancerSemantic proximity Read