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Article

Periostin facilitates ovarian cancer recurrence by enhancing cancer stemness.

Scientific reports - 4 Dec 2023

Huang Zhiqing, Byrd Olivia, Tan Sarah, Hu Katrina, Knight Bailey, Lo Gaomong, Taylor Lila, Wu Yuan, Berchuck Andrew, Murphy Susan K

Abstract excerpt

The lethality of epithelial ovarian cancer (OC) is largely due to a high rate of recurrence and development of chemoresistance, which requires synergy between cancer cells and the tumor microenvironment (TME) and is thought to involve cancer stem cells. Our analysis of gene expression microarray data from paired primary and recurrent OC tissues revealed significantly elevated expression of the gene encoding...

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Share to Cell Adhesion Molecules
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38049490
DOI: 10.1038/s41598-023-48485-8
PMCID: PMC10695946

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