Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Role of junctional intercellular communication in hepatic carcinogenesis in rats].

Bulletin du cancer - 1 Jan 1990

Mesnil M, Yamasaki H

Abstract excerpt

Two major alterations in gap junctional intercellular communication (GJIC) during experimental carcinogenesis have been seen: a decrease of its capacity during tumor promotion and a selective loss of intercellular communication between transformed cells and surrounding normal counterparts. These data, first discovered in our laboratory on mouse fibroblasts (BALB/c 3T3), were partly confirmed in rat liver...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Communication
Share to Cell Transformation, Neoplastic
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Liver Neoplasms, Experimental

Share to Mice, Inbred BALB C

Share to Phenotype

Source

Identifiers

PMID: 2400821

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Role of junctional intercellular communication in hepatic carcinogenesis in rats].PMID 2400821Read ↗

Involvement of gap junctions in tumor suppression: analysis of genetically-manipulated mice.Semantic proximity Read ↗

Defective gap junctional intercellular communication in the carcinogenic process.Semantic proximity Read ↗

Psyllium extracts decreased neoplastic phenotypes induced by the Ha-Ras oncogene transfected into a rat liver oval cell line.Semantic proximity Read ↗

Review Article: Paradoxical Effects of Phenobarbital on Mouse HepatocarcinogenesisSemantic proximity Read ↗

Role of connexin32 and beta-catenin in tumor promotion in mouse liver.Semantic proximity Read ↗

Delayed liver regeneration and increased susceptibility to chemical hepatocarcinogenesis in transgenic mice expressing a dominant-negative mutant of connexin32 only in the liver.Semantic proximity Read ↗

Transgenic disruption of gap junctional intercellular communication enhances early but not late stage hepatocarcinogenesis in the rat.Semantic proximity Read ↗

WY-14,643-mediated promotion of hepatocarcinogenesis in connexin32-wild-type and connexin32-null mice.Semantic proximity Read ↗

Characterization of gap junctional communication-deficient mutants of a rat liver epithelial cell line.Semantic proximity Read ↗

Neoplastic phenotype of gap-junctional intercellular communication-deficient WB rat liver epithelial cells and its reversal by forced expression of connexin 32.Semantic proximity Read ↗

Restoration of gap-junctional intercellular communication in a communication-deficient rat liver cell mutant by transfection with connexin 43 cDNA.Semantic proximity Read ↗

The effect of connexin32 null mutation on hepatocarcinogenesis in different mouse strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.