Article
[Interaction between environment and genetic background in type 2 diabetes: lessons from animal models].
Medecine sciences : M/S - 1 Jan 2000
Bernard Catherine, Della Zuana Odile, Ktorza Alain
Abstract excerpt
The respective roles of predisposing genetic factors and environmental factors in the development of type 2 diabetes (T2D) in obese subjects is poorly documented. Rodent models have been set up in an attempt to better understand of the differential effect of a prolonged metabolic stress induced by a high fat diet on glycaemic control according to the genetic background. In utero growth retardation resulting from...
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