Article
Early-Life Origins of Type 2 Diabetes: Fetal Programming of the Beta-Cell Mass
1 Jan 2011
Abstract excerpt
A substantial body of evidence suggests that an abnormal intrauterine milieu elicited by maternal metabolic disturbances as diverse as undernutrition, placental insufficiency, diabetes or obesity, may program susceptibility in the fetus to later develop chronic degenerative diseases, such as obesity, hypertension, cardiovascular diseases and diabetes. This paper examines the developmental programming of glucose...
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