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Article

Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma.

Investigative ophthalmology & visual science - 27 Sept 2013

Liu Yutao, Allingham R Rand, Qin Xuejun, Layfield David, Dellinger Andrew E, Gibson Jason, Wheeler Joshua, Ashley-Koch Allison E, Stamer W Daniel, Hauser Michael A

Abstract excerpt

PURPOSE: To identify the specific genes in human trabecular meshwork (TM) related to POAG. METHODS: Primary open-angle glaucoma TM specimens were obtained from routine trabeculectomy surgery. Nonglaucomatous control TM specimens were dissected from donor eyes using the same approach as a standard trabeculectomy. All cases were screened for myocilin (MYOC) mutations. Total RNA was extracted, labeled, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24003086
DOI: 10.1167/iovs.13-12128
PMCID: PMC3787658

Genes

MYOC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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