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Gene Expression Profile of the Human Trabecular Meshwork: NEIBank Sequence Tag Analysis

23 May 2003

Abstract excerpt

PURPOSE: To characterize the gene expression pattern in the human trabecular meshwork (TM) and identify candidate genes for glaucoma by expressed sequence tag (EST) analysis as part of the NEIBank project. METHODS: RNA was extracted from dissected human TM and used to construct unamplified, un-normalized cDNA libraries in the pSPORT1 vector. More than 4000 clones were sequenced from the 5' end. Clones were...

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PMID: 12766061
DOI: 10.1167/iovs.02-1099

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