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mtDNA lineage expansions in Sherpa population suggest adaptive evolution in Tibetan highlands.

Molecular biology and evolution - 1 Dec 2013

Kang Longli, Zheng Hong-Xiang, Chen Feng, Yan Shi, Liu Kai, Qin Zhendong, Liu Lijun, Zhao Zhipeng, Li Lei, Wang Xiaofeng, He Yungang, Jin Li

Abstract excerpt

Sherpa population is an ethnic group living in south mountainside of Himalayas for hundreds of years. They are famous as extraordinary mountaineers and guides, considered as a good example for successful adaptation to low oxygen environment in Tibetan highlands. Mitochondrial DNA (mtDNA) variations might be important in the highland adaption given its role in coding core subunits of oxidative phosphorylation in...

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PMID: 24002810
DOI: 10.1093/molbev/mst147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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