Article
Evaluation of the simultaneous effects of KRAS G12V and LCS6 alterations on the behavior of head and neck squamous cell carcinoma.
Mutation research - 1 Jan 2025
Yenigun Vildan Betul, Ucar Vasfiye Betul, Sari Zeynep Betul, Azzawri Ali Ahmed, Acar Yasemin Sena, Kaplan Muhammed Burak, Nergiz Suleyman, Acar Hasan
Abstract excerpt
BACKGROUND: Head and neck squamous cell carcinomas are the seventh most common cancer accounting for 90 % of malignant neoplasia of the upper respiratory system. KRAS is a very important oncogene, leading to the suppression of apoptosis, and promoting the pathogenesis and development of tumors. MicroRNAs (miRNAs) are highly conserved, small noncoding RNA molecules aberrantly expressed in various pathologies...
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