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Article

Immunopathogenic mechanisms of systemic autoimmune disease.

Lancet (London, England) - 31 Aug 2013

Wahren-Herlenius Marie, Dörner Thomas

Abstract excerpt

Systemic lupus erythematosus, Sjögren's syndrome, and dermatomyositis are systemic autoimmune diseases that develop after environmental triggering of genetically susceptible individuals. The precise cellular and molecular mechanisms leading to autoimmune disease, and what factors determine which organs are involved, remain poorly understood. Recent insights into genetic susceptibility now make obvious that...

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PMID: 23993191
DOI: 10.1016/S0140-6736(13)60954-X

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