Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The penetrance of copy number variations for schizophrenia and developmental delay.

Biological psychiatry - 1 Mar 2014

Kirov George, Rees Elliott, Walters James T R, Escott-Price Valentina, Georgieva Lyudmila, Richards Alexander L, Chambert Kimberly D, Davies Gerwyn, Legge Sophie E, Moran Jennifer L, McCarroll Steven A, O'Donovan Michael C, Owen Michael J

Abstract excerpt

BACKGROUND: Several recurrent copy number variants (CNVs) have been shown to increase the risk of developing schizophrenia (SCZ), developmental delay (DD), autism spectrum disorders (ASD), and various congenital malformations (CM). Their penetrance for SCZ has been estimated to be modest. However, comparisons between their penetrance for SCZ or DD/ASD/CM, or estimates of the total penetrance for any of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Aberrations
Share to Developmental Disabilities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Genetic Predisposition to Disease

Share to Genomic variations and chromosomal abnormalities

Share to Penetrance

Share to Schizophrenia

Share to Schizophrenia research and treatment

Source

Open in PubMed Open full text

Identifiers

PMID: 23992924
DOI: 10.1016/j.biopsych.2013.07.022
PMCID: PMC4229045

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The penetrance of copy number variations for schizophrenia and developmental delay.PMID 23992924Read ↗

The Contribution of Mosaic Chromosomal Alterations to Schizophrenia.Semantic proximity Read ↗

Copy number variant syndromes are frequent in schizophrenia: progressing towards a CNV-schizophrenia modelSemantic proximity Read ↗

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.Semantic proximity Read ↗

Association of copy number variation across the genome with neuropsychiatric traits in the general population.Semantic proximity Read ↗

Copy number variation in schizophrenia in Sweden.Semantic proximity Read ↗

High rate of disease-related copy number variations in childhood onset schizophrenia.Semantic proximity Read ↗

Copy number variants in German patients with schizophrenia.Semantic proximity Read ↗

Copy Number Variations in Schizophrenia: Critical Review and New Perspectives on Concepts of Genetics and DiseaseSemantic proximity Read ↗

Comparative Analyses of Copy-Number Variation in Autism Spectrum Disorder and Schizophrenia Reveal Etiological Overlap and Biological Insights.Semantic proximity Read ↗

Penetrance of Neurodevelopmental Copy Number Variants Is Associated With Variations in Cortical Morphology.Semantic proximity Read ↗

CalPen (Calculator of Penetrance), a web-based tool to estimate penetrance in complex genetic disorders.Semantic proximity Read ↗

Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.