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Article

Telomere length is associated with increased risk of cutaneous melanoma: a Mendelian randomization study.

Melanoma research - 1 Dec 2023

Liu Mingjuan, Lan Yining, Zhang Hanlin, Zhang Xinyi, Wu Mengyin, Yang Leyan, Zhou Jia, Tong Meiyi, Leng Ling, Zheng Heyi, Li Jun, Mi Xia

Abstract excerpt

RESULTS: The MR analysis using two TL GWAS datasets revealed strong and consistent evidence that long TL is causally associated with an increased risk of CM. The analysis of the Codd et al. dataset found that long TL significantly predicted an elevated risk of CM (IVW OR = 2.411, 95% CI 2.092-2.780, P = 8.05E-34). Similarly, the analysis of the Li et al. dataset yielded consistent positive results across all MR...

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PMID: 37650705
DOI: 10.1097/CMR.0000000000000917

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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