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Article

Extrasynaptic muscarinic acetylcholine receptors on neuronal cell bodies regulate presynaptic function in Caenorhabditis elegans.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Aug 2013

Chan Jason P, Staab Trisha A, Wang Han, Mazzasette Chiara, Butte Zara, Sieburth Derek

Abstract excerpt

Acetylcholine (ACh) is a potent neuromodulator in the brain, and its effects on cognition and memory formation are largely performed through muscarinic acetylcholine receptors (mAChRs). mAChRs are often preferentially distributed on specialized membrane regions in neurons, but the significance of mAChR localization in modulating neuronal function is not known. Here we show that the Caenorhabditis elegans homolog...

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Source

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Identifiers

PMID: 23986249
DOI: 10.1523/JNEUROSCI.1359-13.2013
PMCID: PMC3756759

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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