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Article

The immunoglobulin super family protein RIG-3 prevents synaptic potentiation and regulates Wnt signaling.

Neuron - 14 Jul 2011

Babu Kavita, Hu Zhitao, Chien Shih-Chieh, Garriga Gian, Kaplan Joshua M

Abstract excerpt

Cell surface Ig superfamily proteins (IgSF) have been implicated in several aspects of neuron development and function. Here, we describe the function of a Caenorhabditis elegans IgSF protein, RIG-3. Mutants lacking RIG-3 have an exaggerated paralytic response to a cholinesterase inhibitor, aldicarb. Although RIG-3 is expressed in motor neurons, heightened drug responsiveness was caused by an aldicarb-induced...

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Identifiers

PMID: 21745641
DOI: 10.1016/j.neuron.2011.05.034
PMCID: PMC3134796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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