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Article

A role for the Erk MAPK pathway in modulating SAX-7/L1CAM-dependent locomotion in Caenorhabditis elegans.

Genetics - 4 Feb 2022

Moseley-Alldredge Melinda, Sheoran Seema, Yoo Hayoung, O'Keefe Calvin, Richmond Janet E, Chen Lihsia

Abstract excerpt

L1CAMs are immunoglobulin cell adhesion molecules that function in nervous system development and function. Besides being associated with autism and schizophrenia spectrum disorders, impaired L1CAM function also underlies the X-linked L1 syndrome, which encompasses a group of neurological conditions, including spastic paraplegia and congenital hydrocephalus. Studies on vertebrate and invertebrate L1CAMs...

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Identifiers

PMID: 34849872
DOI: 10.1093/genetics/iyab215
PMCID: PMC9097276

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A role for the Erk MAPK pathway in modulating SAX-7/L1CAM-dependent locomotion in Caenorhabditis elegans.PMID 34849872Read ↗

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