Spike protein oligomerization control of Semliki Forest virus fusion.

doi:10.1128/JVI.64.10.5214-5218.1990

Back to search

Article

Spike protein oligomerization control of Semliki Forest virus fusion.

Journal of virology - 1 Oct 1990

Lobigs M, Wahlberg J M, Garoff H

Abstract excerpt

We have recently shown, using cleavage-deficient mutants of the p62-E1 membrane protein complex of Semliki Forest virus that p62 cleavage to E2 is necessary for the activation of the fusion function of the complex at pH 5.8 (a pH optimal for virus fusion) (M. Lobigs and H. Garoff, J. Virol. 64:12...

Topics

Animals
Cell Line
Cell Membrane
Kinetics
Macromolecular Substances
Membrane Fusion
Phenotype
Semliki forest virus
Viral Proteins

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.