Article
Association of TP53 mutational status and gender with survival after adjuvant treatment for stage III colon cancer: results of CALGB 89803.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2013
Warren Robert S, Atreya Chloe E, Niedzwiecki Donna, Weinberg Vivian K, Donner David B, Mayer Robert J, Goldberg Richard M, Compton Carolyn C, Zuraek Marlene B, Ye Cynthia, Saltz Leonard B, Bertagnolli Monica M
Abstract excerpt
PURPOSE: The TP53 tumor suppressor is frequently mutated in colon cancer, but the influence of such mutations on survival remains controversial. We investigated whether mutations in the DNA-binding domain of TP53 are associated with survival in stage III colon cancer. EXPERIMENTAL DESIGN: The imp...
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