Article
Gender-specific genomic profiling in metastatic colorectal cancer patients treated with 5-fluorouracil and oxaliplatin.
Pharmacogenomics - 1 Jan 2011
Gordon Michael A, Zhang Wu, Yang Dongyun, Iqbal Syma, El-Khouiery Anthony, Nagashima Fumio, Lurje Georg, Labonte Melissa, Wilson Peter, Sherrod Andy, Ladner Robert D, Lenz Heinz-Josef
Abstract excerpt
AIMS: Survival and response rates in metastatic colorectal cancer remain poor, despite advances in drug development. There is increasing evidence to suggest that gender-specific differences may contribute to poor clinical outcome. We tested the hypothesis that genomic profiling of metastatic colorectal cancer is dependent on gender. MATERIALS & METHODS: A total of 152 patients with metastatic colorectal cancer...
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