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Prevalence of PIK3CA mutations and the SNP rs17849079 in Arab breast cancer patients.

Cancer biology & therapy - 1 Oct 2013

Karakas Bedri, Colak Dilek, Kaya Namik, Ghebeh Hazem, Al-Qasem Abeer, Hendrayani Fawziah, Toulimat Mohamed, Al-Tweigeri Taher, Park Ben Ho, Aboussekhra Abdelilah

Abstract excerpt

Carcinomas initiate and progress due to genetic and epigenetic alterations in epithelial cells. However, recently, these alterations have also been reported in stromal fibroblasts. The gain-of-function mutations in the PI3K p110 catalytic subunit (PIK3CA) have been identified in many cancers with a current global incidence of 26% (18-40%) in breast carcinomas. We analyzed the mutational frequency of PIK3CA of...

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PMID: 23982433
DOI: 10.4161/cbt.25945
PMCID: PMC3926885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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