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Article

Estimation of CYP2D6*10 genotypes on citalopram disposition in Chinese subjects by population pharmacokinetic assay.

Journal of clinical pharmacy and therapeutics - 1 Dec 2013

Chen B, Xu Y, Jiang T, Feng R, Sun J, Zhang W, Yang W, Li J, Adeniyi O, Chen H

Abstract excerpt

WHAT IS KNOWN AND OBJECTIVE: There is great interindividual variability in citalopram (CIT) pharmacokinetics. We attempted to establish a population pharmacokinetic (PPK) model of CIT in Chinese healthy subjects, to evaluate the effect of genetic polymorphism on CIT pharmacokinetics and to compare the PPK and non-compartmental (NCA) assays in the estimation of CIT bioequivalence. METHODS: Blood samples of 23...

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Identifiers

PMID: 23981149
DOI: 10.1111/jcpt.12029

Genes

CIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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