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Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections

26 Aug 2013

Abstract excerpt

When combinatorial antibody libraries are rendered infectious for eukaryotic cells, the integrated antibody genotype and cellular phenotype become permanently linked and each cell becomes a selection system unto itself. These systems should be ideal for the identification of proteins and pathways that regulate differentiation so long as selection systems can be devised. Here we use a selection system based on the...

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PMID: 23980154
DOI: 10.1073/pnas.1313671110

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