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Article

A simple method for isolating and culturing the rat brain microvascular endothelial cells.

Microvascular research - 1 Nov 2013

Liu Yang, Xue Qiang, Tang Qing, Hou Min, Qi Hongyi, Chen Gang, Chen Weihai, Zhang Jifen, Chen Yi, Xu Xiaoyu

Abstract excerpt

Brain microvascular endothelial cells (BMECs), a main component of the blood-brain barrier, play a critical role in the pathogenesis of many brain diseases. The primary culture of BMECs has been used in various models for studying cerebrovascular diseases in vitro. However, there are still several problems existing in the isolation and cultivation of primary rat BMECs, such as low yield, contamination with other...

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PMID: 23978334
DOI: 10.1016/j.mvr.2013.08.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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