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[The binding mechanisms of F VIII Trp1707Ser mutation-associated inhibitor].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Aug 2013

Wu Xi, Lu Ye-ling, Ding Qiu-lan, Dai Jing, Xi Xiao-dong, Wang Hong-li, Wang Xue-feng

Abstract excerpt

OBJECTIVE: To investigate the binding mechanisms of FVIII Trp1707Ser mutation-associated inhibitor. METHODS: The APPT, PT, TT, Fg and FVIII:C were detected to make phenotypic diagnosis of haemophilia A. Inhibitors titer were measured by Bethesda method. Long distance-PCR (LD-PCR) and sequence-specific PCR were adopted for screening the intron 22 and intron 1 inversions respectively. FVIII coding and boundary...

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PMID: 23978021
DOI: 10.3760/cma.j.issn.0253-2727.2013.08.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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