Article
GISTogram: a graphic presentation of the growing GIST complexity.
Virchows Archiv : an international journal of pathology - 1 Oct 2013
Ricci Riccardo, Dei Tos Angelo Paolo, Rindi Guido
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. They have represented a paradigm of molecular-targeted therapies for solid tumors since the discovery of KIT mutations and KIT expression in GIST in 1998, which opened the way to the use of imatinib, a tyrosine kinase inhibitor able to inhibit the growth of cells expressing KIT-mutant isoforms. Since...
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