Article
Chemokines and atherosclerosis: focus on the CX3CL1/CX3CR1 pathway.
Acta pharmacologica Sinica - 1 Oct 2013
Apostolakis Stavros, Spandidos Demetrios
Abstract excerpt
Atherosclerosis is currently considered an inflammatory disease. Much attention has been focused on the potential role of inflammatory mediators as prognostic/diagnostic markers or therapeutic targets of atherosclerotic cardiovascular disease. CX3CL1 (or fractalkine) is a structurally and functionally unique chemokine with a well documented role in atherosclerosis. In its membrane bound form it promotes the firm...
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