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Article

Introduction of silent mutations in a codon-optimized xylanase (xynB) results in enhanced protein expression in HEK293A cells.

Biotechnology letters - 1 Dec 2013

Liu Zhiguo, Feng Tao, Ji Qianqian, Cong Peiqing, Chen Yaosheng, He Zuyong

Abstract excerpt

Xylanase is used extensively to improve feed conversion rates to enhance the performance of poultry and pigs. By expressing xylanase in simple-stomached animals, new breeds of genetically modified animals with enhanced feed conversion rates may be obtained. However, expression of heterologous proteins derived from lower organisms in mammalian cells is usually inefficient. When common codons of a ''one amino...

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PMID: 23974494
DOI: 10.1007/s10529-013-1311-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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