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Article

Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.

Biological psychiatry - 15 Aug 2012

Greenwood Tiffany A, Akiskal Hagop S, Akiskal Kareen K, Kelsoe John R

Abstract excerpt

BACKGROUND: The many attempts to identify genes for bipolar disorder (BD) have met with limited success, which has generally been attributed to genetic heterogeneity and small gene effects. However, it is also possible that the categorical phenotypes used in genetic studies of BD are not the most informative or biologically relevant. Although quantitative phenotypes provide an alternative to categorical...

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Identifiers

PMID: 22365631
DOI: 10.1016/j.biopsych.2012.01.018
PMCID: PMC3925336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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