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Article

A multivariate analysis of 59 candidate genes in personality traits: the temperament and character inventory.

Clinical genetics - 1 Nov 2000

Comings D E, Gade-Andavolu R, Gonzalez N, Wu S, Muhleman D, Blake H, Mann M B, Dietz G, Saucier G, MacMurray J P

Abstract excerpt

Cloninger (Cloninger CR. Neurogenetic adaptive mechanisms in alcoholism. Science 1987: 236: 410-416) proposed three basic personality dimensions for temperament: novelty seeking, harm avoidance, and reward dependence. He suggested that novelty seeking primarily utilized dopamine pathways, harm avoidance utilized serotonin pathways, and reward dependence utilized norepinephrine pathways. Subsequently, one...

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Identifiers

PMID: 11140838
DOI: 10.1034/j.1399-0004.2000.580508.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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