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Oncogenic chromosomal translocations and human cancer (Review)

20 Aug 2013

Abstract excerpt

Chromosomal translocations are very common in human cancer. The molecular mechanisms of chromosomal translocations are complex and are not fully understood. Recent studies showed organization of genomes is higher-order in the nucleus and every chromosome or chromatin has its preferential position and territory. These findings suggest the spatial arrangements of chromosomes and gene loci in the interphase nucleus...

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PMID: 23970180
DOI: 10.3892/or.2013.2677

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