Article
[The Trp64Arg polymorphism of beta3-adrenoreceptor gene study in persons with overweight and obesity].
Voprosy pitaniia - 1 Jan 2012
Baturin A K, Pogozheva A V, Sorokina E Iu, Makurina O N, Tutel'ian V A
Abstract excerpt
The development of obesity is determined by lifestyle and genetic mechanisms. In particular, the polymorphisms in the adrenergic receptor genes (ADRB) have been extensively studied for association with obesity-related phenotypes. ADRB3 is an obvious candidate gene given its involvement in the regulation of lipolysis and thermogenesis. ADRB3 Trp64Arg polymorphism, a missense mutation in the first transmembrane...
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