Article
ADRB3 polymorphism rs4994 (Trp64Arg) associates significantly with bodyweight elevation and dyslipidaemias in Saudis but not rs1801253 (Arg389Gly) polymorphism in ARDB1.
Lipids in health and disease - 27 Mar 2018
Daghestani Maha, Daghestani Mazin, Daghistani Mamoon, Eldali Abdelmoneim, Hassan Zeinab K, Elamin Maha H, Warsy Arjumand
Abstract excerpt
BACKGROUND: In some populations, obesity and body weight related disorders show a correlation with polymorphisms in three subtypes of beta-adrenoceptor (β1, β2, and β3) [ADRB1, ADRB2 and ADRB3] genes. We scanned for the polymorphism of Arg389Gly (rs1801253) in ADRB1 and Trp64Arg (rs4994) in ADRB3 genes in Saudi population to determine association, if any, of these polymorphisms with obesity and related disorders....
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